P-116: Adalimumab in refractory paediatric ulcerative colitis
نویسندگان
چکیده
منابع مشابه
Adalimumab for refractory peripheral ulcerative keratitis
Peripheral ulcerative keratitis (PUK) is an immune-mediated disorder characterized by patchy, peripheral stromal thinning and infiltrates which tend to coalesce and extend to the limbus and often the sclera (unlikeMooren's ulcer) even in the presence of an intact overlying epithelium [1]. PUK is usually associated with systemic disorders such as rheumatoid arthritis, inflammatory bowel disease,...
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Approximately 15% of patients with ulcerative colitis will have a severe attack requiring hospitalisation for intravenous steroids at some stage in their illness. Sixty per cent of patients treated with corticosteroids will be symptom free by the end of five days, 15% will have significant improvement, and 25% will not improve. Those who fail to improve may be treated with intravenous cyclospor...
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Extracolonic involvement of the gastrointestinal tract is extremely uncommon in ulcerative colitis (UC) and rarely found in the upper gastrointestinal tract or in postoperative cases since it typically responds to steroids. Here we report a case of UC complicated by extensive ileal inflammation that was refractory to steroids. A 20-year-old man was diagnosed with UC of typical pancolitis withou...
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OBJECTIVE To evaluate cost-utility of infliximab and adalimumab for the treatment of moderate-to-severe ulcerative colitis (UC) refractory to conventional therapies in Canada. METHODS A Markov model was constructed to evaluate incremental cost-utility ratios (ICUR) of 5 mg/kg and 10 mg/kg infliximab and adalimumab therapies compared to 'usual care' in treating a hypothetical cohort of patient...
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ژورنال
عنوان ژورنال: Journal of Crohn's and Colitis
سال: 2014
ISSN: 1873-9946
DOI: 10.1016/s1873-9946(14)50144-4